Lin P, Alexander RA, Liang CH, et al. Zdzieblik D, Oesser S, Gollhofer A, Knig D. Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides. Learn more about collagen vs. biotin. To protect collagen stores, doctors recommend you use a broad-spectrum sunscreen with an SPF of 30 or higher every day, refrain from, Topical creams which include retinoic acid or, Despite the well-known risks of exposure to. HHS Vulnerability Disclosure, Help Can diet help improve depression symptoms? Jendricke P, Centner C, Zdzieblik D, Gollhofer A, Knig D. Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial. In the cosmetic industry, marine collagen is one of the most popular types, as it causes less inflammation than animal sources and is less likely to contain Brain Behav. 8600 Rockville Pike PMC Would you like email updates of new search results? Use of hyaluronic acid fillers for the treatment of the aging face. Collagen is the most abundant protein in the human body. Having, high levels of calcium in your blood is also known as hypercalcemia, and seems to be more predominantly an issue in women., Whether collagen can cause headaches or not is a great question to be asking, especially when trying to decide which supplements are right for you and your body. Bagheri Miyab K, Alipoor E, Vaghardoost R, et al. HHS Vulnerability Disclosure. Copper Peptides Can Collagen Cause Diarrhea? Unauthorized use of these marks is strictly prohibited. Molecules 2021;26(7):2021. 2018;17(2):298-304. Other supplements like magnesium may also have a similar effect to too much calcium., Most collagen users benefit from the additional boost in calcium absorption as it can improve bone density among other things. Glutamate receptor-subtype antagonists are effective in preclinical models of migraine, and in the clinic. -CTX and P1NP were unaffected by CP supplementation (P > 0.05). Bone turnover; Collagen; Exercise recovery; Hydrolyzed collagen; Inflammation; Muscle soreness. Possible side effects include: Upset stomach Diarrhea Rashes, or skin reactions Nausea Constipation Heartburn Headache 2010;340(5):360-6. The site is secure. Is the ketogenic diet right for autoimmune conditions? WebMD does not provide medical advice, diagnosis or treatment. Collagen supplements have the potential to cause both headaches and migraines. 2018 Apr;15(2):361-370. doi: 10.1007/s13311-018-0616-5. ANSWER: Collagen and biotin supplements appear to be getting attention in the media for promoting healthy aging, along with joint and bone health. Kumar S, Sugihara F, Suzuki K, Inoue N, Venkateswarathirukumara S. A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis. Zehra A, Burns J, Liu CK, et al. A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. If you take too much collagen, it can throw off the balance of amino acids in your body and lead to side effects such as headaches, digestive issues, and fatigue. However, it is important to understand what collagen and biotin are and what research is available to support these claims. Are they safe, and do they work? Collagen 2021;20(1):188-194. Complement Ther Med. Many people take collagen supplements to add more collagen to their diet. Hakuta A, Yamaguchi Y, Okawa T, Yamamoto S, Sakai Y, Aihara M. Anti-inflammatory effect of collagen tripeptide in atopic dermatitis. Br J Nutr. View abstract. An official website of the United States government. MNT is the registered trade mark of Healthline Media. ANSWER: Collagen and biotin supplements appear to be getting attention in the media for promoting healthy aging, along with joint and bone health. We include products we think are useful for our readers. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. One thing that you can look for is a medical grade collagen supplement like ProT Gold., It is still a possibility that you may experience some side effects with any collagen supplement. So, these additional things are more often associated with certain side effects like an upset stomach. An official website of the United States government. Although they are most popularly used to combat the signs of aging in the skin, collagen peptides can provide a number of other potential benefits as well. This means that the manufacturer has broken the collagen in the supplements down into peptides, making it easier for the body to absorb and use. Peptides for Skin: Benefits, What to Look for, and Side Effects5 Collagen Side Effects You Need to Know About by Zen Principle As with any supplement, collagen supplements do have some potential side effects, especially when taken in excess. 5. Collagen Peptides Having high levels of calcium in your blood is also known as hypercalcemia and seems to be more predominantly an issue in women., Too much calcium can also cause some skin rashes and other symptoms overlapping with side effects with collagen., One way to determine if calcium is the cause of your headaches or if taking a collagen supplement is raising your blood calcium levels is to get a blood test for calcium. 2020;7:580918. Int J Sport Nutr Exerc Metab. 2022 Dec;52(12):2889-2908. doi: 10.1007/s40279-022-01718-8. Collagen is a protein that promotes skin elasticity. The effects of collagen peptides on muscle damage - PubMed Accessibility Our team thoroughly researches and evaluates the recommendations we make on our site. sharing sensitive information, make sure youre on a federal Hexsel D, Zague V, Schunck M, Siega C, Camozzato FO, Oesser S. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Porfrio, E. & Fanaro, G. B. Unfortunately, our bodies produce about 1% less collagen 1 with each passing year, and we're eCollection 2022. The https:// ensures that you are connecting to the However, it is possible to have too much of a good thing., If calcium is the cause of your collagen-related headache problems, then a simple change in collagen supplement dosage may be in order to reduce the likelihood that your collagen can cause headaches., If you are worried about or already are experiencing headaches from your collagen supplements then it is best to consult a medical professional. Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. These types of ingredients and additives found in supplements can also be a reason why someone gets a headache versus the collagen molecules themselves., Next, looking at the absorption rate can help you avoid other side effects like bloating or an upset stomach. Before Manufacturers tend to produce them using the bones and protein of animals. Can Collagen Cause High Triglycerides. Arch Acad Emerg Med 2021;9(1):e50. J Cosmet Dermatol. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Nutr Res 2018;57:97-108.View abstract. Collagen eCollection 2022 Aug. FOIA But does collagen have any side effects, and can collagen cause headaches?. Int J Dermatol 2021;60(12):1449-1461. 2021;20(3):825-834. 2020;72(3):125-130. Camilion JV, Khanna S, Anasseri S, Laney C, Mayrovitz HN. Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides on Volumetric and Areal Bone Mineral Density, Bone Geometry and Bone Turnover in Postmenopausal Women With Osteopenia. 2022 Oct 11;8(1):126. doi: 10.1186/s40798-022-00522-y. Most collagen supplements are not vegan or vegetarian friendly. Collagen supplements may help support skin, hair, and joint health. Other potential side effects of collagen peptides in individuals with sensitivities or for those using poor quality collagen products include the following: If you are sensitive to the free glutamic acid found in collagen protein, you may experience mild headaches or have difficulty sleeping. WebGlutamate is implicated in cortical spreading depression, trigeminovascular activation, and central sensitization. Best overall collagen supplement: Vital Proteins Collagen Peptides. The researchers found that the women taking the calcium and the collagen had lower levels of a protein responsible for breaking down bones in their blood. The .gov means its official. This is typically due to Looking older: fibroblast collapse and therapeutic implications. View abstract. WebCollagen is a nutritional supplement made from animal or fish materials. There is some evidence to back these claims up. Prowting JL, Bemben D, Black CD, Day EA, Campbell JA. Lampropoulou-Adamidou K, Karlafti E, Argyrou C, et al. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 2015;95(4):702-7. However, it is However, scientists have not fully studied all the alleged benefits. If you experience any adverse reactions after taking collagen, stop taking it and speak to your Hydroxyproline ingestion and urinary oxalate and glycolate excretion. View abstract. Lopez HL, Ziegenfuss TN, Park J. The participants engaged in regular exercise for 12 weeks. This group saw a significant reduction in artery stiffness and a reduction in their low-density lipoprotein, or bad, cholesterol levels. Heart failure: Could a low sodium diet sometimes do more harm than good? J Med Food. The effects of collagen peptides on muscle damage, inflammation and bone turnover following exercise: a randomized, controlled trial. de Miranda RB, Weimer P, Rossi RC. Please enable it to take advantage of the complete set of features! Integr Med (Encinitas). 2022 Aug 4;14(8):e27666. What exactly is the reason collagen can cause a headache? Most collagen users do not experience any adverse effects when taking a high-quality collagen supplement at the proper dosage., The source of the collagen is also a huge factor in whether or not collagen can cause headaches and other side effects., For instance, many bone broth based collagen supplements are very high in sodium and potassium, not to mention the collagen in that type of supplement is harder to digest.. Background: Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density. Some other potential things that collagen may help with include: Collagen supplements come in a variety of types. Whether used as a powder in smoothies or as oral supplements, collagen has all the rage nowadays. Lee SK, Posthauer ME, Dorner B, Redovian V, Maloney MJ. There are some reports that collagen supplements may cause other digestive side effects, such as heartburn and feelings of fullness ( 21 ). View abstract. ProT Powder Collagen Protein - 32 Servings. Sibilla S, Godfrey M, Brewer S, Budh-Raja A, Genovese L. An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. Collagen makes up a significant amount of bone structure and helps keep the bones strong. Collagen for Weight Loss Looking at the ingredients we find, they are natural, gluten-free, non-GMO, dairy-free, grass-fed pasture-raised cows, and wild-caught fish, and cage-free chickens. Expert Opin Investig Drugs. Collagen side effects may, for instance, be a result of excessive collagen intake. Would you like email updates of new search results? Aguirre A, Gil-Quintana E, Fenaux M, Erdozain S, Sarria I. J Diet Suppl. However, some vegan and vegetarian collagen options are available. and transmitted securely. Type of ingredient: Hydrator and strengthener 4. Collagen Peptides Dolan E, Dumas A, Keane KM, Bestetti G, Freitas LHM, Gualano B, Kohrt WM, Kelley GA, Pereira RMR, Sale C, Swinton PA. Sports Med. 2013;77(4):691-6. There is some evidence to suggest that collagen supplements can help with restoring or preventing the deterioration of the cartilage in the joints. Jacob Y, Anderton RS, Cochrane Wilkie JL, Rogalski B, Laws SM, Jones A, Spiteri T, Hince D, Hart NH. Yes. Side Effects of Collagen Peptides on Skin, Digestion, and Oral collagen supplementation for skin aging: A fad or the future? official website and that any information you provide is encrypted Bethesda, MD 20894, Web Policies Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study. 2017 Dec 14;12(12):CD009789. 2019 Mar 4. Elam ML, Johnson SA, Hooshmand S, et al. Oral Intake of Collagen Peptide Attenuates Ultraviolet B Irradiation-Induced Skin Dehydration In Vivo by Regulating Hyaluronic Acid Synthesis. Of those side effects, there has been a recurring theme among many collagen users asking: can taking collagen cause headaches? So, it is important to get to know proper dosage of collagen for your body and nutritional needs., No matter the supplement that you decide to use, there is always a potential for side effects or adverse reactions. Collagen supplements have the potential to cause both headaches and migraines., According to a few case studies on using collagen to treat osteoarthritis, when participants were using the collagen supplement, they did report a lower pain level in their joints but among the most commonly reported side effects was a headache from time to time.. Over time, however, the production of this protein slows down. migraine Careers. Jung K, Kim SH, Joo KM, et al. Nutrients. Does Collagen Make You Poop More? ANSWERED J Musculoskelet Neuronal Interact. All rights reserved. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. pii: E892. Collagen Protein and Sport: Alternative Sources and Strategies for Bioactive and Sustainable Sports Nutrition. Allergic Reaction. View abstract. Many believe that collagen supplements can help reduce the effects of aging, such as by adding moisture to the skin, reducing wrinkles, and improving elasticity. Unfortunately, experts say that the research supporting all of these claims is limited. Its always something Before People can consume collagen supplements they purchase from a number of online and local stores, and they can usually find a type that matches their specific dietary needs. The following are the most common types of collagen a person can find in stores or online: Most supplements will contain several of these, and possibly other, types of collagen. Rheumatoid arthritis, lupus, dermatomyositis and scleroderma are autoimmune, connective tissue diseases known to damage collagen. Maia Campos PMBG, Melo MO, Siqueira Csar FC. Int J Mol Sci. Keywords: Additionally, collagen contains various animal proteins, which can cause allergic reactions in some people. Appl Physiol Nutr Metab. Physiological, Pathological, and Circadian Factors Impacting Skin Hydration. Can If you buy through links on this page, we may earn a small commission Heres our process. These include: Collagen peptide supplements can offer a range of benefits from improved skin health to a reduction in joint pain and stronger hair and nails. View abstract. While we have no reports of ProT Gold users experiencing headaches or migraines after using our collagen products, preliminary research into the topic suggests that there may be a correlation between some collagen supplements and headaches., Whether collagen can cause headaches or not often is dependent on the person taking the supplement, the dosage, the type of collagen, and the supplement quality itself., If you suspect that your supplemental collagen can cause headaches or migraines, then exploring why you have this reaction and how to prevent it will be the first place to start., Before we get into whether collagen can cause headaches, lets look at the overall safety of collagen supplements in general., If youre asking the question: can collagen cause headaches? You are probably also interested in other possible side effects of collagen, and if collagen is a safe supplement to take., Its hard to answer whether collagen can cause headaches and if the supplement itself is safe, simply because the FDA does not regulate most supplements., Since there is such limited regulation of supplements on the market, this leads to immense skepticism regarding how safe they really are and what side effects they cause., The lack of regulation when it comes to supplements versus drugs means that not all supplement companies necessarily have to prove their claims., So, if they are simply trying to sell a product to the consumer, they do not have to have evidence to support whether or not the collagen supplement they are providing actually will benefit the consumer, or whether their supplemental collagen can cause headaches or other issues., Still, the FDA does recognize ingestible collagen as Generally Recognized As Safe (GRAS)., There have been specific collagen supplements that have been recalled by the FDA for safety reasons, which is why it is important to buy from a reputable brand., For instance, our liquid collagen supplement, ProT Gold, is actually recognized as a medical food, which is why it has a nutritional label, not a supplement label., Because of this, ProT Gold is also trusted by over 3,000 medical facilities and used widely for medical nutrition therapy., Something that should be recognized about collagen as a supplement is that it is natural.
